|
|
ATP + biotin-carboxyl-carrier_protein + HCO3- <=> ADP + phosphate + carboxybiotin-carboxyl-carrier_protein
|
6.3.4.14
biotin carboxylase
6.4.1.1
pyruvate carboxylase
|
–
–
|
|
BRENDA:
BR135
KEGG:
R04385
SABIO-RK:
4080
|
|
|
|
(7R,8S)-diaminononanoate + CO2 + ATP <=> dethiobiotin + phosphate + ADP + H+
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
BRENDA:
BR128
KEGG:
R03182
MetaCyc:
DETHIOBIOTIN-SYN-RXN
SABIO-RK:
3011
|
|
|
|
S-adenosyl-L-methionine + (8S)-8-amino-7-oxononanoate <=> S-adenosyl-4-methylthio-2-oxobutanoate + (7R,8S)-diaminononanoate
|
2.3.1.47
8-amino-7-oxononanoate synthase
2.6.1.62
adenosylmethionine---8-amino-7-oxononanoate transaminase
|
–
–
|
|
BRENDA:
BR47441;
BS406980
KEGG:
R03231
MetaCyc:
DAPASYN-RXN
SABIO-RK:
3057
|
|
|
|
carboxyl-carrier_protein + biotin + ATP <=> diphosphate + AMP + biotin-carboxyl-carrier_protein + H+
|
6.3.4.15
biotin---[biotin carboxyl-carrier protein] ligase
|
–
|
|
BRENDA:
BR136
MetaCyc:
BIOTINLIG-RXN
|
|
|
|
biotin-carboxyl-carrier_protein <=> biotin-carboxyl-carrier_protein_(dimer)
|
0.0.0.0
|
–
|
|
BRENDA:
BR52895
|
|
|
|
dethiobiotin + sulfur + 2 S-adenosyl-L-methionine <=> biotin + 2 L-methionine + 2 5''-deoxyadenosine
|
2.8.1.6
biotin synthase
|
–
|
|
BRENDA:
BS398860
|
|
|
|
carboxybiotin-carboxyl-carrier_protein + acetyl-CoA <=> biotin-carboxyl-carrier_protein + malonyl-CoA
|
2.1.3.15
acetyl-CoA carboxytransferase
6.4.1.2
acetyl-CoA carboxylase
|
–
–
|
|
BRENDA:
BR52249
KEGG:
R04386
SABIO-RK:
4081
|
|
|
|
pimeloyl-[acyl-carrier_protein] + L-alanine + H+ <=> (8S)-8-amino-7-oxononanoate + CO2 + [acyl-carrier_protein]
|
2.3.1.47
8-amino-7-oxononanoate synthase
|
–
|
|
BRENDA:
BR44048
KEGG:
R10124
MetaCyc:
RXN-11484
|
|